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In vitro and in vivo analyses highlight its primary metabolite, Ac-LKKTE, as exhibiting the most pronounced activity related to cellular repair, with other metabolites such as Ac-LKK and Ac-LK exhibiting longer persistence but reduced bioactivity

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phase 2 program for DD01, a long-acting dual GLP-1 and glucagon receptor agonist being tested over 48 weeks in metabolic dysfunctionassociated steatotic liver disease (MASLD) and metabolic dysfunctionassociated steatohepatitis (MASH)

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