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Over the past twenty years, number of investigations has been carried by different research groups to establish the role of 5ARI in the management of prostate cancer [44]

UA not only acts as a radical scavenger but also interacts with other antioxidant systems, such as superoxide dismutase (SOD), which eliminates superoxide from the cell [36]

Exercise-Induced Oxidative Stress Intense or prolonged exercise generates substantial oxidative stress through increased oxygen consumption and metabolic rate, increased mitochondrial electron leakage producing reactive oxygen species, recruitment of inflammatory immune cells to exercising muscles, and mechanical stress on tissues producing oxidative damage

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