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FIGURE 1 This chemical architecture integrates the inherent stability of the steroidal framework with the functional versatility of side chain/glycosyl substituents, endowing caudatin with the ability to interact with multiple molecular targets such as uPA (Urokinase-Type Plasminogen Activator), MMP9 (Matrix Metalloproteinase 9), and JAK2 (Janus Kinase 2) ( 2.2 Structural stability The rigid architectural framework of the caudatin steroidal scaffold, in conjunction with the chemical microenvironment of specific functional groups, serves as the foundational basis for its biological activity

doi: 10.1183/09031936.00.15104100, 7

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