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(2007) found that H2A de-ubiquitinase (2A-DUB) interacts with the histone acetyltransferase (HAT) p300/CBP-associated factor (p/CAF) to form an enzymatic complex, which could help HATs provide optimized substrates for 2A-DUB to remove the ubiquitin from H2A

For example, in one multi-center study, almost one-half of young HCV-infectedinjection drug users had moderate or severe depression198

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