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In comparison to the placebo group, more participants in the semaglutide group stopped taking the medication due to gastrointestinal problems

More serious reactions, though rare, include signs of infection (increasing warmth, redness, swelling, purulent drainage, or fever) or allergic responses (widespread rash, difficulty breathing, or facial swelling)

Weight loss improves metabolic markers, but the cellular machinery for processing energy, meaning mitochondrial function, may need separate support, particularly in individuals with long-standing metabolic dysfunction

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