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Likewise, all isoforms possess four EF hand domains, and a single C2 domain that flank the X and Y catalytic core

With good compatibility and targeting, the product can be used in combination with chemotherapeutic agents, immunotherapeutic drugs, etc., showing synergistic effects in preclinical studies

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Combined nicotinamide N-methyltransferase inhibition and reduced-calorie diet normalizes body composition and enhances metabolic benefits in obese mice