Kubo, I
Over time, diets high in fat and sugar can alter the lining of the duodenum, changing how the body processes food and regulates hormones
biochemically, there is intracellular glutathione (GSH) depletion and decreased activity of glutathione peroxidase 4 (GPX4), lipid peroxides cannot be metabolized by the GPX4-catalyzed reduction reaction, and Fe 2+ oxidizes lipids in a Fenton-like manner, resulting in a large amount of ROS, which promotes ferroptosis 3,6
Understandably, the first question most new clients ask, is is it safe?
Your doctor can submit the appeal with clinical documentation of your body mass index (BMI), weight-related comorbid condition, and previous weight loss attempts to demonstrate medical necessity