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In a subgroup of patients that became hypoglycemic during the baseline mixed meal challenge, across all doses of mizagliflozin (combined), compared with baseline, the glucose nadir was raised by 19.3 mg/dL (38%) (p=0.03), the glucose peak was lowered by -36.3 mg/dL (21%) (p=0.03), and the insulin peak was lowered by -324.5 IU/mL (53%) (p=0.016)

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There is also a growing distinction between indications within coverage frameworks

They also interact with certain pain medications and can worsen post-operative nausea

Readouts are expected primarily in 2026 and 2027