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Key areas of impact Skin, hair, nails Copper peptides such as GHK-Cu, as well as other peptides used topically, have broad applications in cosmetics, especially for improving skin health

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Authors Contributions TTG, SM, and JTA conceived the overall concept, contributed to the writing of the manuscript, conducted the literature search, and supervised the manuscript development

The most common issues are cosmetic and mild: transient stinging or redness, dryness, and occasionally a faint bluish or brownish tint on the skin from the copper, particularly at higher concentrations