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Among other things, the companies failed to adequately test medicine components for diethylene glycol (DEG) or ethylene glycol (EG) contamination before using them

The result at week 68: Continued semaglutide 2.4 mg: lost an additional 7.9% of body weight (total loss from baseline: 17.4%) Switched to placebo: regained 6.9% of body weight (net loss from baseline: 5.0%) Thats a roughly 15-point difference in body weight between the two groups at the end of the trial, attributable entirely to whether the medication continued

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If tolerated well and improvements continue, they may maintain or cautiously increase to 300400 mcg every other day or daily depending on individual response

Nonalcoholic fatty liver disease and obesity: an obesity medicine association (OMA) clinical practice statement (CPS) 2022