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Weight changes are usually small and take time, and the medication works best when paired with sustainable habits like balanced meals, movement, and good sleep

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Alcohol consumption is inversely associated with adherence to diabetes self-care behaviours

Weight loss continued until the end of the 56 weeks, and approximately 50% of patients experienced 5% more weight loss than they had experienced at 28 weeks

Insulin receptor activation increases gene expression and levels of PGC-1, which in turn increases the transcription factor Nrf1, which activates key genes that drive mitogenesis