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Phosphorylation of key signaling proteins like Akt, mTOR, and S6K occurs rapidly and can be measured using cell-level biology techniques

Further, LR3 IGF-I forms crucial ternary complexes with integrins (ITGAV:ITGB3 and ITGA6:ITGB4) and IGFR1, essential for comprehensive IGF1 signaling, influencing the phosphorylation and activation of IGFR1, MAPK3/ERK1, MAPK1/ERK2, and AKT1

The truth is you would probably need to use IGF 1 LR3 in conjunction with other Peptides and Androgens to get the best results

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This is not something you can control or test for clinically, but it explains why two people on identical protocols can have different outcomes