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The difference in concentration patterns (lower peaks, higher troughs) is modest enough that major safety divergence seems unlikely

This is often temporary and goes away on its own

Frontiers in bioscience

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Approved by the MHRA in June 2026 as the first oral GLP-1 medicine licensed in the UK for weight loss, it is prescription-only, taken once daily on an empty stomach, and offered after clinical assessment against BMI-based eligibility as an adjunct to a reduced-calorie diet and increased physical activity