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In the randomized placebo-controlled HOME trial of 390 adults with type 2 diabetes (de Jager and colleagues, Long term treatment with metformin in patients with type 2 diabetes and risk of vitamin B-12 deficiency, BMJ, 2010), metformin lowered serum B12 by a mean of 19 percent over 4.3 years
Pfizer/Hospira: the pharmaceutical benchmark Pfizer (through its Hospira subsidiary) is the most-cited manufacturer of USP bacteriostatic water in pharmaceutical references, trial protocols, and community documentation
How can I get on a GLP-1
One important consideration: a 5mg vial reconstituted with 2mL of water gives you excellent measurement precision at the 1mg dose level (40 units, very easy to read), but the 4mg dose would require 160 units, far exceeding the syringe
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