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Sitagliptin works ONLY when blood sugar is elevated, to address diminished insulin levels due to -cell dysfunction and uncontrolled production of glucose by the liver (due to pancreatic -cell and -cell dysfunction) Figure

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Acetylation refers to the process of transferring an acetyl group to a side chain group of an amino acid, and acetylation of glutathione is usually the attachment of an acetyl group to an active sulfur atom