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In this context, we present and discuss the outcomes of the most recent trials investigating the impact of SGLT2 inhibitors and GLP-1-R agonists on renal and cardiovascular outcomes in patients, both with and without T2DM

Understanding how GLP-1 works in the brain has become increasingly relevant as GLP-1 receptor agonist medicationslicensed in the UK for type 2 diabetes and weight managementproduce neurological effects including appetite suppression and potential neuroprotective benefits

Ethics declarations Conflict of interest AFB, VBS, FGDF and STF have no conflicts of interest that are directly relevant to the content of this article

Depression and Anxiety Management Client experiences: Reduced anxiety levels and panic episodes More stable moods throughout the day Better emotional regulation Increased confidence from both physical and mental improvements Cardiovascular Health Beyond Weight Loss Many clients report cardiovascular improvements that seem to exceed what weight loss alone would provide

Manufacturer copayment savings cards available online on Eli Lillys and Novo Nordisks websites may be beneficial for commercially insured patients