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They are usually mild and resolve as the body adjusts to the medication

Comparing to Novo Nordisk, our simaglutide API has lower impurity

If serious gastrointestinal symptoms occur, the dose may be delayed or reverted to the previous dose until symptoms resolve

Step-by-Step Instructions for Taking Oral Semaglutide Oral semaglutide must be taken on an empty stomach, at least 30 minutes before eating, drinking (except water), or taking other medications

Updated This article was originally published on February 26, 2026, and has been updated to reflect Novo Nordisks voluntary dismissal of all claims asserted in its case against Hims & Hers without prejudice.