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By scavenging reactive oxygen species (ROS), these compounds mitigate oxidative stress, which is a key driver of metabolic dysfunction in chronic diseases like diabetes and cardiovascular disorders [61, 62]

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Hence, differences observed in vitro for AX inactivation with thiol-containing antioxidants can be ascribed to the different number of thiol groups in the molecules used, one in GSH and N-acetyl-L-cysteine and two in DTT