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It is a complex and multifaceted disease that involves a variety of factors

Deciphering the Janus-faced nature of the Apolipoprotein superfamily in parkinsonian neurodegeneration: molecular crosstalk between the Astroglial Secretome and neuronal homeostasis

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Potential areas of expansion include: Cardiovascular outcomes: A dedicated CVOT, if not already required as a post-marketing commitment, would evaluate whether orforglipron reduces MACE in patients with established cardiovascular disease or high cardiovascular risk, following the precedent set by the SELECT trial for semaglutide