Without knowing the details underlying these events, the rationale for some of them appears reckless, the authors conclude
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In addition, there was a significant down-regulation in apoptosis initiator caspase 8 and caspase 9, apoptosis effector caspase 3, and apoptosis promotion protein Bax, but up-regulation in apoptosis resistance protein Bcl2 and proliferation protein proliferating cell nuclear antigen (PCNA) in PDGF-BB induced PASMCs group when compared to control group
doi:10.1186/s12929-017-0390-4
Keywords: glucagon-like peptide-1 receptor agonists, psychiatric adverse events, disproportionality analyses, FAERS database, pharmacovigilance study Introduction Diabetes has been one of the fastest growing public health issues worldwide in recent decades