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Van Can J, Sloth B, Jensen CB, Flint A, Blaak EE, Saris WHM

Conversely, patients who carry variants in hydroxysteroid 17-beta dehydrogenase 13 (HSD17B13, rs72613567) and mitochondrial amidoxime-reducing component 1 (MARC1, rs2642438) are more protected than the general population (48, 49)

Application in Studies of NNMTRelated Energy Metabolism Mechanisms Given its core advantage of selectively inhibiting NNMT and regulating NAD+ synthesis, 5-amino-1-methylquinolinium injection serves as a foundational tool for investigating the role of NNMT in energy metabolism and dissecting the molecular pathways of metabolic disorders

doi: 10.1038/s41467-019-09234-6 29 LiebermeisterWNoorEFlamholzADavidiDBernhardtJMiloR

T., Nguyen, Q