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Estrogen is proposed to exert its effects through activation of the MAP kinase pathway and transcription factor NF-B, leading to increased expression of antioxidant enzymes such as superoxide dismutase (Farhat et al., 2017

These proteins undergo minimal turnover as the lens ages

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Taken together, this work reinforces guidance to ensure adequate micronutrient intake before and during pregnancy and suggests that standard supplements may help lower autism risk