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PEG 3350 is often a safe and effective choice for constipation caused by GLP-1

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Slower gastric emptying means glucose enters your bloodstream more gradually, preventing the rapid spikes that trigger cravings

We performed both operations without removing or replacing the intrathecal catheter, taking care not to damage the intrathecal catheter or spinal cord

Drug class Orlistat: Gastrointestinal lipase inhibitor Wegovy: GLP-1 receptor agonist Active ingredient Orlistat Wegovy: Semaglutide Mechanism Orlistat: Blocks fat absorption in the gut (~30% dietary fat) Wegovy: Reduces appetite and food intake via central and hormonal pathways Dosing frequency Orlistat: Oral capsule (taken with meals) Wegovy: Once-weekly injection Weight loss efficacy Orlistat: ~5-10% average body weight reduction Wegovy: ~1015% average body weight reduction Clinical use Orlistat: Lower-intensity, oral option Wegovy: High-efficacy, first-line injectable therapy for obesity management Which weight loss injection is most effective