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However, the authors note that substantial weight loss can be accompanied by reductions in lean body mass, underscoring the need for further research into dosing strategies and interventions that preserve muscle while promoting fat loss

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2 D 3 in the serum, but VDR expression can be down-regulated by pathogenic species such as Salmonella typhimurium in the intestine (Wu et al., 2010)

It also avoids GIP receptor agonism, whose metabolic consequences remain somewhat controversial (GIP has been characterized as both insulinotropic and adipogenic depending on context)