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The preclinical research is not trivial, and legitimate questions about potential applications in tendon repair, gut healing, and neuroprotection merit serious investigation
However, according to the EFSA, the risk of developing alopecia, an early sign of chronic Se toxicity, is increased even with Se intakes of 330 g/day (130 g/day from the background diet plus 200 g/day from supplements) (51)
The compounds dimethyl sulfoxide and dimethyl sulfone were also present and it was suggested that they modify the aroma to give it a sweet edge