Visible changes in body composition (fat reduction, muscle tone) typically become apparent after 612 weeks of consistent use, combined with appropriate training and nutrition
Individual safety findings for one molecule dont necessarily predict class-wide effects, says Finer, safety signals often relate to specific structural features or off-target activities rather than the primary mechanism of action. He thinks oral GLP-1 drugs have the potential for better dose titration, which might help control the current, mainly gastrointestinal, side-effects of the injectable peptides
There is also so much GLP1 noise: social media onslaught, ads, workplace discussions, doctor office pressures, the list goes on
This concept is supported by several studies demonstrating that the intestinal microbiome plays a critical role in serotonin metabolism, bile acid production, and even intestinal motility (5961)
it's a marathon