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Characteristics such as unhealthy nutrition habits, sedentary lifestyle as well as visceral obesity, in combination with diabetes, can contribute to other metabolic disorders

The consensus of regulatory and independent reviews by 2014 was that current evidence does not confirm an increased risk of pancreatitis or pancreatic cancer with GLP-1 therapies ( [64] ) ( [124] )

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Approved for use in the United States since 2017, it has recently seen a surge in popularity attributed to reports of off-label use for weight- loss promotion

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