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For drug treatment, DFP (75 mg/kg, intraperitoneally, synthesized in China Peptides Co., Ltd., Shanghai, China) or DMT1i (50 mg/kg, orally, MedChemExpress, China) [19, 20] was administered to the animals 1 h before GA daily for three consecutive days

Using a mouse model of polygenic T2D, we demonstrate that chronic glibenclamide therapy does more than simply reduce insulin secretion

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