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Interestingly, in addition to proper supplementation support, another recommended treatment for cerebral folate deficiency is a dairy-free diet (something I advocate for in Hashimotos too), as mammalian milk is thought to contribute to folate receptor antibodies, and may block folate transport to the brain

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Topical is excellent for localized skin benefits and is what most commercial skincare products use

after excluding other causes of the disease, it is feasible to explore the existence of mutations linked to PFIC in adults with adult-onset cryptogenic cholestasis (ACC) [21]