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MiR-122 was the first miRNA identified as tissue-specific, and it is the most abundant in liver involved in lipid metabolic reprogramming 83

Unilateral attachment of the orbicularis oris to the medial crura footplates, anterior nasal spine, and caudal septum on the noncleft side exacerbates the columellar tilt and contributes to deviation of the caudal septum toward the noncleft side

This is because TNSALP accounts for a significant percentage of total ALP activity, particularly in the extracellular environment

DHA@MIL-101 NRs self-disassembled in the acid microenvironment to dissociate Fe 3+ , achieving GSH consumption-mediated redox reaction and Fe 2+ -mediated Fenton reaction (Figure 5D)

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