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In rat pinealocytes (the melatonin-producing cells of the pineal gland), Epitalon was shown to upregulate both AANAT (arylalkylamine N-acetyltransferase, the rate-limiting enzyme in melatonin production) and pCREB (a transcription factor involved in melatonin gene expression)

Semaglutide Semaglutide is the peptide used in medications like Ozempic and Wegovy

Analysis was performed using Oroboros Datlab 7 ( and further normalization was done to correct for day-to-day variations by normalizing to the average maximal respiration of the sham group for each day

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