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The most common reason for iron overload in patients with hematologic diseases is the administration of multiple red blood cell transfusions representing a massive excess of iron uptake with about 200 mg of iron in one unit of packed red blood cells ( Independent of red blood cell transfusions, disease-immanent factors can contribute to the iron overload phenotype

First methylglyoxal with GSH forms hemithioacetal, which is the substrate of Gly I

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Engaging in physical activity, both intensive movement improvement and increased muscle strength do not occur without side effects, resulting in accelerated tissue wear, especially in professional athletes, where excessive use affects areas where tissues are genetically less valuable and prone to frequently occurring, cumulative micro-injuries

Injections can bypass the digestive system, ensuring adequate absorption