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ESWL (extracorporeal shock wave therapy): Although the exact mechanism of action is not fully understood, it causes direct damage to the plaque, leading to resorption through vascularization and cavitation

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Similarly, serotonin levels are significantly lower in the model group, indicating a potential sleep disorder

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The selective mechanism that avoids systemic hormonal disruption suggests potential for extended use compared to interventions that create metabolic or endocrine imbalances requiring periodic breaks