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Rare but notable: repeated use can occasionally cause focal skin darkening (hyperpigmentation), particularly on the face

Marine-derived natural products have also emerged as viable therapeutic candidates in AD, with GV-971 demonstrating both clinical relevance and low toxicity

Recommended sites include the abdomen (at least 2 inches from the belly button), the front or outer thigh, and the outer back of the upper arm (with assistance)

Astragaloside IV protects against cisplatin-induced liver and kidney injury via autophagy-mediated inhibition of NLRP3 in rats