Thus, the glycolysis pathway would be downregulated and gluconeogenesis would be upregulated
13 Diabetic kidney disease begins with damage to the small blood vessels that supply the kidneys
In time, progression from NAFLD to fibrosis (scarring) and cirrhosis (scarring of the liver) can result in hepatorenal syndrome, a complication marked by severe kidney malfunction with reduced kidney blood flow and abdominal edema (ascites)
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