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Other hepatokines also contribute to the metabolic dysfunction seen in MASLD: Angiopoietin-like protein 3 inhibits lipoprotein lipase activity, promoting dyslipidemia and insulin resistance, while fibroblast growth factor 21, though elevated in MASLD, shows reduced efficacy due to hepatic insulin resistance

TeleSlims physician-led evaluation includes pre-prescription checks such as medical history review, assessment for contraindications, and ordering labs when clinically indicated to confirm baseline safety