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Regulatory functions of L-carnitine, acetyl, and propionyl L-carnitine in a PCOS mouse model: focus on antioxidant/antiglycative molecular pathways in the ovarian microenvironment

Beyond its role in serotonin synthesis, tryptophan plays a central role in the kynurenine pathway, a metabolic pathway critical for the production of nicotinamide adenine dinucleotide (NAD+), a molecule essential for ATP generation in cellular metabolism (Savitz, 2020) (Figure 5)

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With a few notable exceptions, such as the ventral hippocampus, this projection pattern largely matches the distribution pattern of GLP1 receptorexpressing cells (Trapp & Cork, 2015), which might be indicative of these receptors throughout the CNS mainly being exposed to brainderived GLP1

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