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Research suggests that long-term usemore than two years of continuous useof PPIs can lead to lower serum levels of vitamin B12

"The results from this landmark study across 37 countries provide strong evidence that semaglutide can help patients with MASH by not only improving liver health, but also addressing the underlying metabolic issues that contribute to the disease," says Arun Sanyal, a professor of medicine at Virginia Commonwealth University

MOTS-C works by enhancing mitochondrial metabolism

The combination produced 24.2% weight loss at the 12mg dose in Phase 2 trials, the highest reported for any GLP-1 class medication so far