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This can lead to direct damage to cellular organelles including mitochondria

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Nature 266:565567 Xu D, Trmulot L, Yang Z, Mhamdi A, Chtel-Innocenti G, Mathieu M, Espinasse C, Van Breusegem F, Vanacker H, Issakidis-Bourguet E, Noctor G (2025) Cytosolic monodehydroascorbate reductase 2 promotes oxidative stress signaling in Arabidopsis

Here is a practical example

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