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Furthermore, different from the ordered -helical ECL1 in inactive GLP-1R 33 and -hairpin in inactive GCGR 36 that cover the binding pocket and probably block peptide insertion, ECL1 of active GLP-2R, GLP-1R and GCGR simultaneously move outward and stand upwards in line with TM2 and TM3

Patent intelligence is a competitive weapon

Skipping or shortening it produces weaker, less durable results

*Correspondence: Jiteng Wang, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Then, during one of my midnight "research sessions"