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Kidney cortices were dissected, sliced, minced, and shaken at 37 C for 1 h in a 0.25% trypsin/EDTA solution

In addition to these findings, a systematic review and network meta-analysis of data from 36,186 patients with CKD associated with T2D demonstrated a 57% reduction in the risk of hyperkalemia with an SGLT2i added to an MRA compared with MRA alone (relative risk, 0.43 [0.23 to 0.79]) [82]

[DOI] [PMC free article] [PubMed] [Google Scholar] 60.Minohara M, Matsuoka T, Li W, et al

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10.1042/bsr20180549 58 LiY.GuoY.TangJ.JiangJ.ChenZ