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However, in a retrospective study of 559 patients with nonsmall cell lung cancer (NSCLC) given nivolumab or pembrolizumab, 231 (41%) developed irAEs, and 40 (17.4%) presented multiple-site irAEs

There is a deeper irony embedded in this practice: if buyers believed these products were safe, properly characterized and manufactured to the standards expected of pharmaceutical-grade products, they would not need to commission independent purity tests

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These effects are generally mild and self-limiting, representing the intended normalization of digestive processes rather than adverse reactions

Toward a molecular basis for affective disorders