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Gradual dose reduction over 4-8 weeks allows the body to readjust, and thyroid levels should be checked both during and after the taper, since weight stabilization changes levothyroxine requirements once again

Zadik Z, Chalew SA, McCarter RJ, Jr., Meistas M, Kowarski AA

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doi: 10.3389/fmicb.2017.01804 133 WuH.RebelloO.CrostE

Over 68 weeks, with a starting dose of 2 mg escalated every 4 weeks: 9 mg dose: 26.4% average body weight reduction (29.1 kg / 64.2 lbs) 12 mg dose: 28.7% average body weight reduction (32.3 kg / 71.2 lbs) Placebo: 2.1% average body weight reduction The milestone achievements tell an even more compelling story