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The patients who will do best on these medications over the long term are those who use them within a framework that protects lean mass, supports metabolic health, and addresses the behavioural and physiological underpinnings of weight regain

It is known that the acute HPA response to stress plays an important role and has numerous functions which promote cells survival, but chronic activation of this axis by stressful episodes may lead to a wide range of pathological conditions, including depression

But what if one of the biggest barriers, strict dosing requirements, suddenly disappeared

10.1152/ajpendo.1997.273.5.E981 82

Scott Butsch, who is director of obesity medicine at the Cleveland Clinic in Ohio, who was not involved in the research