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The loss of HNF1A and FXYD2 may induce membrane hyperpolarization, thereby impairing insulin secretiona mechanism relevant to both maturity-onset diabetes of the young type 3 (MODY3) and T2D (Weng et al., 2023)

The outer thigh, midway between the hip and the knee, is a reliable subcutaneous injection site and is the preferred alternative when the abdomen is uncomfortable or if site rotation requires a break from abdominal injections

Some people may have mild side effects, such as redness, swelling, or tenderness at the injection site

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