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Melanosomes, subcellular lysosome-like organelles in melanocytes, synthesize two types of melanin, the brownish-black eumelanin and the reddish-yellow pheomelanin [4]

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Hives Symptoms With an outbreak of hives, you may notice: Raised welts of varying sizes on the skin Welts that are reddish in color (this may be harder to see on dark skin) The welts itch intensely, often at night Welts come and go over minutes or hours You may also have angioedema, symptoms of which include: Puffy face, eyelids, ears, mouth, hands, feet, and genitals Swelling on one side of the body Discomfort where the swelling has happened Changes in skin color Hives and Contact Dermatitis Contact dermatitis is a painful or itchy rash you get after your skin touches something you're allergic to (allergic contact dermatitis) or that's otherwise irritating to your skin (irritant contact dermatitis)

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