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We outline new mechanistic concepts, future therapeutic opportunities, potential for differentiation from currently available medicines and areas of uncertainty requiring additional investigation

So if you're eating carbohydrates, you'll stimulate insulin secretion, which will tell the blood, yeah, won't facilitate uptake glucose and keep blood sugar stable and it'll convert some of the glucose at the fat for storage

What side effects should be expected

Adequate fiber prevents constipation, feeds beneficial gut bacteria, stabilizes blood sugar, and creates satiety from smaller portions

-blockers, particularly nonselective ones, can diminish the first phase of insulin secretion from pancreatic cells, potentially due to the inhibition of 2-mediated insulin release (Sarafidis and Bakris, 2006)