snATAC-seq specifically aids in the prediction of cell-type-specific transcription factor activity and identification of distant regulatory regions that influence gene transcription 16
GI losses, the use of diuretics, hemorrhages, and endocrine impairments such as adrenal insufficiency, ACTH (adrenocorticotropic hormone) deficit, or severe hypothyroidism are common causes of low sodium levels
doi:10.1007/bf02284971
March of Dimes Birth Defects Foundation, New York Daniels T, Gallagher M, Tremblay G, Rodgers RL (2004) Effects of valproic acid on cardiac metabolism
However, most body tissues are in equilibrium with the blood that constantly perfuses them, and there is no known mechanism whereby benzodiazepines could be locked up in tissues such as the brain