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GHRH pulses primarily determine the amplitude of GH secretory bursts by maintaining somatotroph GH synthesis capacity and directly stimulating release during permissive periods when somatostatin tone is low

Lindqvist gratefully acknowledges support from the Swedish Research Council (2015-00387), Marie Sklodowska Curie Actions, Cofund (Project INCA 600398), the Swedish Society of Medicine, the Sderstrm-Knigska Foundation, the Sjbring Foundation, and OM Persson Foundation and the province of Scania (Sweden) state grants (ALF)

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