Gardocki said she developed the product after realizing there was no skin care specifically formulated to enhance the effects of red-light therapy
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Introduction Atopic dermatitis (AD) is one of the most common chronic inflammatory cutaneous diseases with a relapsing-remitting course characterized by pruritus, dry skin, and eczema lesions ( Among all of the inflammatory cytokines, TNF- has gained a lot of attention due to its multiple effects in promoting cells death, including receptor-interacting protein 1 (RIP1)-independent apoptosis, RIP1-dependent apoptosis (RDA), and necroptosis ( As the main bioactive component of tea polyphenols, the health benefits of epigallocatechin-3-gallate (EGCG) have been widely used in treating a wide range of diseases, based on its anti-inflammatory and antioxidant properties ( However, the low bioavailability, instability, and cytotoxicity at a large dose limited the clinical application of EGCG
Later on, in other investigations it was proved that the glycine synthesis in pigs, humans, and other mammals is through the abovementioned three pathways [8]
